Causes
of Bell's (Facial) Palsy
Once thought to be of idiopathic origin,
viral and bacterial infections, and autoimmune disorders such as AIDS
have emerged as the most frequent common causes in the etiology of Bellšs
Palsy.
HERPES SIMPLEX 1
Herpes Simplex 1, was first believed to be a cause of Bell's Palsy during the 1970's. Although some causes Bells palsy are still
considered idiopathic, over twenty years later, a 1995 study (Murakami,
et al.) strongly linked the herpes simplex virus (HSV-1) as the most frequent
cause of Bell's palsy, responsible for at least 60 - 70% of cases. Current
research continues to reinforce his conclusion.
Exposure to HSV-1 has become increasingly common;
a vast majority of the population has been exposed.
§
Most people
are exposed during childhood.
§
Kissing
between relatives is the most frequent source of exposure, but it may
be possible that the virus is also spread while sharing towels, utensils,
etc.
The active virus is commonly associated with
cold sores, but the virus often runs its course without causing any blisters
- blisters actually appear only 15% of the time.
§
HSV-1
is infectious for a short time following the incubation period.
§
This results
in a large population of HSV-1 carriers are unaware they've been exposed
to the virus.
§
It then
enters a dormant state, residing on nerve tissue where several triggers can cause the dormant
virus to reactivate.
As a normal function to remove harmful foreign
bodies such as viruses and bacteria so that we can recover from illness
and injuries, when the latent virus reactivates at the facial nerve, the
immune system begins to produce antibodies.
§
The production
of antibodies causes inflammation.
§
The nerve
itself becomes inflamed, or the inflammation within the canal exerts pressure
on the nerve.
If the location of the inflammation is within
the fallopian canal, there is no room for the swelling to expand.
§
The result
is that the nerve is compressed inside its bony tube.
§
Compression
of the nerve is the injury that stops transmission of signals to muscles.
§
Unable
to receive signals to contract and relax, the muscles become temporarily
weakened or paralyzed.
The triggers for reactivation of the virus
prior to the onset of Bell's palsy have not been proven conclusively However,
impaired immunity, due to temporary (stress, lack of sleep, minor
illness, physical trauma, upper respiratory infection, etc.) or long-term
stressors (autoimmune syndromes, chronic disease, etc.) are now strongly
believed to be the most likely triggers.
OTHER CAUSES ...
Facial and surgical wounds, trauma due to a
blunt force, temporal bone fractures, brain stem injuries, acoustic neuromas,
cysts and tumors can result in facial palsy. Diabetes and thyroid conditions
are also associated with facial palsy. Lupus, Sjogrens syndrome and congenital
defects can, infrequently, cause facial paralysis.
Other VIRAL LINKS
There has been research implicating other viruses,
including cytomegalovirus, Epstein-Barr, rubella and mumps, in the etiology
of Bell's palsy. As with the herpes virus, potential triggers appear to
be related to conditions that affect the immune system. The internal process
that would cause the nerve to become compressed and result in Bells palsy
is currently thought to be the same as described above for the Herpes
virus.
This
website was created by Nancy Velazquez, a graduate student at Hunter College
Department of Communication Sciences. It is a requirement for the Neuroprocesses
of Communication Course COMSC 712. November 12, 2003.